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Symbol
Name
ID

Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
MGI:96285

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Anosmia

EEG abnormality

Abnormal nonverbal communicative behavior

Delayed speech and language development

Lack of spontaneous play

Impaired ability to form peer relationships

Autism

Addictive alcohol use

Hyperactivity

Attention deficit hyperactivity disorder

Inflexible adherence to routines

Motor stereotypy

Restrictive behavior

Intellectual disability

Excessive daytime somnolence

Obstructive sleep apnea

Snoring

Seizure

Focal impaired awareness seizure

Disease(s) Associated with SLC6A4

alcohol dependence

attention deficit hyperactivity disorder

autistic disorder

obstructive sleep apnea

Mouse Phenotypes

abnormal enteric nervous system morphology

abnormal enteric neuron morphology

abnormal brain morphology

increased brain weight

abnormal barrel cortex morphology

abnormal neurite morphology

abnormal serotonergic neuron morphology

abnormal nervous system electrophysiology

abnormal action potential

abnormal neuron physiology

abnormal neurotransmitter uptake

Availability

Mouse Genotype

Slc6a4^tm1.1Rbl/Slc6a4^tm1.1Rbl

Slc6a4^tm1Grch/Slc6a4^tm1Grch

Slc6a4^tm1Kpl/Slc6a4^tm1Kpl

Slc6a4^tm2.1Rbl/Slc6a4^tm2.1Rbl

Slc6a4^tm1Kpl/Slc6a4⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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